I wait for the low cost high capacity battery, a power cell that can store one thousand amperes (one million Milli amperes) and cost less than £25. Electric cars would become very cheap and houses could store surplus solar power to use overnight. At the moment lithium iron power cells are very expensive. The ones that power cars cost as much as a small car on their own. Electricity would become very cheap overall, perhaps as low as 4 pence per killowatt-hour, at the moment most Brits pay about 10 pence per killowatt-hour.
I also wait for the cure to Alzheimer's disease, that is a brain disease that causes a person's memory to stop working. I met a person that didn't even know their own name and they didn't know where they lived, it is a very nasty disease and can be cured if someone finds a way to remove the damaged proteins that build up on the brain tissue.
Then there is cancer, everyone knows how bad cancer is. If there was a drink that kills all cancer cells without harming the healthy ones then that would be an amazing breakthrough.